Microsoft Research Forum is a virtual series highlighting purposeful research and its real-world impact, from fundamental exploration to advancing AI responsibly, scaling innovation through products and open source, and driving positive change for society.

Up next: Season 2 | Episode 1

Wednesday, September 24, 2025 | 8:00 AM – 9:00 AM Pacific Time

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Agenda

Mojan Javaheripi
Mojan Javaheripi
Member of Technical Staff
Microsoft Research AI Frontiers

TALK | IMPACT AT SCALE

Pushing boundaries of complex reasoning in small language models

This talk explores Phi-4-Reasoning and Phi-4-Reasoning-Plus—two 14B models designed to push the boundaries of complex reasoning in small language models. By introducing a dedicated “thinking block” into the model response and applying supervised fine-tuning and reinforcement learning on carefully curated, reasoning-intensive STEM datasets, we achieved significant advances in the models’ problem-solving capabilities.

Kwangjun Ahn
Kwangjun Ahn
Senior Researcher
Microsoft Research AI Frontiers

TALK | MISSION ON AI

Dion: The distributed orthonormal update revolution is here

We introduce Dion, an orthonormal-update optimizer in the style of Muon that adds a tunable rank axis—orthonormalizing only the top-r subspace via amortized power iteration—to retain Muon’s fast convergence while significantly reducing compute and communication, and scaling efficiently with FSDP/TP for very large models.

Paolo Costa
Paolo Costa
Senior Principal Research Manager
Microsoft Research Cambridge

TALK | NEW ADVANCEMENT OUT OF THE LAB

Disrupting AI Datacenters with MicroLEDs

The performance of modern AI systems is increasingly constrained by limitations in memory and network resources, driven by fundamental scaling challenges in current communication technologies. Copper links are power-efficient and reliable but have very limited reach (< 2 m). Optical links offer longer reach but at the expense of high-power consumption and lower reliability. A collaborative effort across MSR, Azure Networking, Azure Hardware, and M365 has been investigating the use of microLEDs to develop a novel technology that can break this trade-off by providing high-distance connectivity with low power consumption, low cost, and high reliability, opening up exciting opportunities for radical new AI cluster designs.

Frank Noé
Frank Noé
Partner Research Manager
Microsoft Research AI for Science

TALK | AI FOR ALL

Scalable emulation of protein equilibrium ensembles with BioEmu

The next frontier in molecular biology is predicting how biomolecules change shape to drive biological function, a key step for drug discovery. MSR AI for Science’s Biomolecular Emulator (BioEmu) recently reached a major milestone, emulating protein structure changes and stabilities with near-experimental accuracy while running up to 100,000x faster than traditional simulations.

Alexandra Olteanu
Alexandra Olteanu
Principal Researcher
Microsoft Research Montréal
Su Lin Blodgett
Su Lin Blodgett
Senior Researcher
Microsoft Research Montréal

TALK | RESEARCH EXPLORATION

Dehumanizing Machines: Making Sense of AI Systems that Seem Human

GenAI systems are the focus of growing scrutiny in part because they are increasingly anthropomorphic—i.e., they are designed or perceived to be human-like. Guiding practitioners in appropriately and deliberately designing anthropomorphic AI systems requires equipping them with clarity regarding what about these systems’ design and behavior makes them anthropomorphic, and which design decisions and system behaviors are desirable and effective.

Maya Murad
Maya Murad
Senior Technical Program Manager
Microsoft Research AI Frontiers

Host remarks

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