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Medical, health, and genomics

Digital pathology helps decode tumor microenvironments for precision immunotherapy. GigaPath is a novel vision transformer that can scale to gigapixel whole-slide images by adapting dilated attention for digital pathology. In joint work with Providence and UW, we’re sharing Prov-GigaPath, the first whole-slide pathology foundation model pretrained on large-scale real-world data, for advancing clinical research and discovery.

GigaPath: Whole-Slide Foundation Model for Digital Pathology

Research Forum Ep2 | Panel | Transforming the Natural Sciences with AI

Research Forum 2 | Panel Discussion: Transforming the Natural Sciences with AI

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Scaling early detection of esophageal cancer with AI

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Microsoft Health Futures

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Published Date

Publication

Boosting GPT Models for Genomics Analysis: Generating Trusted Genetic Variant Annotations and Interpretations through RAG and fine-tuning

Shuangjia Lu, Erdal Cosgun

Bioinformatics Advances | February 2025

Microsoft Research Blog

Research Focus: Week of January 27, 2025

January 31, 2025

In this issue: A new approach to multimodal pretraining for remote sensing; Managed-retention memory for the AI era; Improving detection of macular telangiectasia type 2; Generalizing symbolic automata.

Publication

LLaVA-Rad MIMIC-CXR Annotations

Juan Manuel Zambrano Chaves (juanza), Shih-Cheng Huang, Yanbo Xu, Hanwen Xu, Naoto Usuyama (naotous), Sheng Zhang, Fei Wang, Yujia Xie, Mahmoud Khademi, Ziyi Yang, Hany Awadalla, Julia Gong, Houdong Hu, Jianwei Yang, Chunyuan Li, Jianfeng Gao, Yu Gu, Cliff Wong, Mu-Hsin Wei, Tristan Naumann, Muhao Chen, Matthew P Lungren, Akshay Chaudhari, Serena Yeung, Curtis Langlotz, Sheng Wang, Hoifung Poon

January 2025

Publication

A generative model for inorganic materials design

Claudio Zeni, Robert Pinsler, Daniel Zügner, Andrew Fowler, Matthew Horton, Xiang Fu, Zilong Wang, Aliaksandra Shysheya, Jonathan Crabbé, Shoko Ueda, Roberto Sordillo, Lixin Sun, Jake Smith, Bichlien Nguyen, Hannes Schulz, Sarah Lewis, Chin-Wei Huang, Ziheng Lu, Yichi Zhou, Han Yang, Hongxia Hao, Jielan Li, Chunlei Yang, Wenjie Li, Ryota Tomioka, Tian Xie

Nature | January 2025

Publication

Enhanced Macular Telangiectasia Type 2 Detection: Leveraging Self-Supervised Learning and Ensemble Models

Shahrzad Gholami, Lea Scheppke, Meghana Kshirsagar, Yue Wu, Rahul Dodhia, Roberto Bonelli, Irene Leung, Ferenc B Sallo, Alyson Muldrew, Catherine Jamison, Tunde Peto, Juan M. Lavista Ferres, Bill Weeks, Martin Friedlander, Aaron Lee, Lowy Medical Research Institute

Ophthalmology Science | January 2025

Project

Publication

Exploring Scalable Medical Image Encoders Beyond Text Supervision

Fernando Pérez-García, Harshita Sharma, Sam Bond-Taylor, Kenza Bouzid, Valentina Salvatelli, Maximilian Ilse, Shruthi Bannur, Daniel Coelho de Castro, Anton Schwaighofer, Matthew P Lungren, Noel Codella, Stephanie Hyland, Javier Alvarez-Valle, Ozan Oktay

Nature Machine Intelligence | January 2025, Vol 7: pp. 119-130

Download Project

Dataset Source Code

DEDector

In this work, we developed a low-cost, smartphone-based automated Non-Invasive Break-Up Time (NIBUT) measurement prototype. It can be used to estimate dryness of the eye. We utilized the 3D-printed Placido ring attachment on a smartphone’s…

GitHub Project Publication

Publication

BioAgents: Democratizing Bioinformatics Analysis with Multi-Agent Systems

Nikita Mehandru, Amanda K. Hall, Olesya Melnichenko, Yulia Dubinina, Daniel Tsirulnikov, David Bamman, Ahmed Alaa, Scott Saponas, Venkat S. Malladi

January 2025

Publication

BioAgents: Democratizing Bioinformatics Analysis with Multi-Agent Systems

Nikita Mehandru, Amanda K. Hall, Olesya Melnichenko, Yulia Dubinina, Daniel Tsirulnikov, David Bamman, Ahmed Alaa, Scott Saponas, V. Malladi

January 2025

Publication

Benchmarking uncertainty quantification for protein engineering

Kevin P. Greenman, Ava P. Amini, Kevin Kaichuang Yang

PLOS Computational Biology | January 2025, Vol 21

Medical, health, and genomics

Highlights